Genomics and Next Generation Sequencing - Continuing Professional Development

نظرة عامة على البرنامج

Students will learn to interpret biological data, analyze it using both command-line and web-based tools, and integrate diverse data types for biological understanding. The module is assessed through written exams and a group presentation.

مخطط البرنامج

Degree Overview:

This module will introduce the students to various sides of Omics:

• Genomics
• Transcriptomics
• Methylation
• Transcription factors analysis
• Chromatin accessibility analysis (e.g.
DNase-seq, ATAC-seq)
• Chromatin structure analysis (e.g.
HiC, ChIA-PET) It will include a coverage of the technological progress:
• History: Sanger sequencing through array technologies
• Next generation Sequencing
• Advanced library construction procedures for specialized assays (e.g.
ChIP, DNase, ATAC, HiC, eCLIP) This module will as well address specific fields of:
• Classical Genetics
• Population Genetics
• Cancer Genomics
• Analyse the various types of data generated in the field both with command line and web interface such as Galaxy
• Integrate the various type of data to understand the biological implication of the results

Assessment:

The module is assessed by a combination of a written examination (60%) in the form of short answer questions and a group presentation (40%) during the course of the module. There will also be a formative written examination in the form of MCQ during this module.

Other:

• Module lead: Professor Jean-Baptiste Cazier
• Please note module is only available as part of MSc Bioinformatics and the International Doctoral Training Programme.