Advanced Sequencing Informatics and Genome Assembly

Program Overview

This five-day course at Cranfield University focuses on advanced sequencing informatics and genome assembly. Participants learn to optimize sequence assembly algorithms, develop de-novo genome assemblies, and apply graph theory in biological data analysis. The program aims to provide a system-level understanding of biological systems and responses to internal and external factors through data integration and analysis.

Program Outline

Advanced Sequencing Informatics and Genome Assembly Course

Degree Overview:

This five-day course at Cranfield University delves into the integration of advanced NGS and 3GS sequencing data with functional annotation. It leverages graph theories for various assemblers like de-Bruijn and Overlap-layout consensus. The program utilizes core platform technologies to offer insights into omic-scale/big-data-driven life sciences. Participants gain a system-level understanding of biological systems and responses to internal and external factors.

Learning Outcomes

• Critically assess data quality limitations based on underlying biological and experimental assumptions.
• Optimize short and long reads sequence assembly algorithms.
• Develop de-novo genome assemblies for diverse species.
• Create in-silico gene prediction models and functional annotation.
• Apply graph theory in biological data analysis.

Core Content

• Research methodologies in genome bioinformatics and interdisciplinary life sciences.
• Advanced Java programming.
• Graph theory applications with Java.
• Advanced next-generation sequencing informatics.
• De-novo genome assembly.
• Gene prediction and functional annotation.

Outline:

The program structure and schedule are not explicitly detailed in the provided context.

Assessment:

Assessment details, including methods and criteria, are not provided in the given text.

Teaching:

Teaching methods, faculty information, and unique approaches are not explicitly mentioned in the context.

Careers:

Career paths, opportunities, and outcomes associated with completing the program are not specified in the text.

Other:

• Cost: £1,400.
• Duration: Five days.
• Location: Cranfield University campus.
• Speaker: Professor Fady Mohareb.
• Participants can gain Cranfield credits applicable towards selected Cranfield degrees.
• Accommodation options are available on-campus or at nearby hotels.
• Travel details and location information are provided.

Additional Points:

• The course aims to develop a system-level understanding of biological systems and responses to various factors through data integration and analysis.
• It utilizes graph theory concepts widely used in assemblers like de-Bruijn and Overlap-layout consensus.
• The program offers insights into big-data driven life sciences using advanced sequencing technologies.