Microbial Genomics Workshop

Program Overview

This one-day workshop introduces clinical microbiology applications of next-generation sequencing (NGS).

Program Outline

Degree Overview:

• Overview: This one-day workshop provides hands-on practical experience on next-generation sequencing (NGS) and its applications in clinical microbiology.
It covers how to analyze and manage NGS data generated by modern sequencing technologies.
• Objectives: By the end of the course, delegates will be able to:
• Understand NGS and its applications in clinical microbiology
• Understand NGS data: Reading raw sequence data and quality control
• Interpret outbreak investigation using NGS
• Identify microbial resistance

Outline:

• Course Structure:
• Introduction to NGS and their applications in clinical microbiology (lecture)
• Working with NGS data: Raw sequence data and quality control (computer lab)
• Outbreak investigation using NGS (lecture)
• De novo assembly: From raw reads to whole genome (lecture & computer lab)
• From assembled genomes to detection of antibiotic resistance in bacteria, monitoring resistance in HIV and HBV, detection of virulence genes, detection of mobile genetic elements (MGEs) such as plasmids, bacteriophages.

Teaching:

• Faculty: Dr Manal Mohammed, PhD in Medical Microbiology from the University of Liverpool, UK.
Her research interests include applying next-generation sequencing technologies and associated bioinformatics analysis tools in investigating the molecular basis of virulence of non-typhoidal salmonellosis in humans and understanding the complex dynamics of bacteria-phage interaction. She is also a fellow at the Higher Education Academy and teaches Microbiology, Medical Microbiology, and Microbial Genomics across a wide range of undergraduate and postgraduate modules.
• Accessibility: The University of Westminster has created online Disabled Access Guides for its buildings in collaboration with AccessAble.